Test reports for Wellisair device WADU-02

One of the great applications of Wellisair technology is virus removal. These can be divided into two large families: enveloped viruses and viruses without envelope. The main difference between them is that the enveloped viruses have a protein matrix that surrounds the nucleic acid (virus genetic information, RNA). Despite what might be expected, that matrix is sensitive to external agents such as oxidation.

The Advanced Oxidation Process (POA) of Wellisair India based on hydroxyl radicals, allows attacking the two types of viruses, but in a different way:

  • Enveloped virus: the hydroxyl radicalsreleased by Wellisair products react with the fatty acid chains in the envelope (lipid reaction). This reaction breaks the membrane, a fact that produces an antioxidant reaction in the virus that accelerates its destruction (indirect protein oxidation reaction produced by lipid peroxidation) by altering its genetic information.

Alters the genetic information of viruses and bacteria (lipid peroxidation reaction):

  • us without envelope: the oxidation directly attacks the genetic information of the virus (direct protein oxidation produced by ROS), making it useless and touched by death.

In order to determine the effectiveness of the Wellisair technology, different tests on various viruses and with different humidity conditions were carried out at the Laboratory of virus contaminating water and food at the University of Barcelona:

  • Syncytial RSV

  • Graph 1. Decrease in the concentration of RSV Syncytial plaque forming units per millilitre (PFU / ml) in dry medium

  • Graph 2. Percentage reduction in the concentration of Syncytial VRS plaque forming units in dry medium.

  • Rotavirus:

  • Graph 3. Decrease in the concentration of Rotavirus plaque forming units per millilitre (PFU / ml) in dry medium

  • Graph 4. Percentage of reduction of the concentration of plaque forming units of Rotavirus in dry medium.

  • Coxsackievirus:

  • Graph 5. Decrease in the concentration of Coxsackievirus plaque forming units per millilitre (PFU / ml) in dry medium.

  • Graph 6. Percentage reduction in the concentration of Coxsackievirus plaque forming units in dry medium.

The results of these tests ensure Wellisair works well against virus elimination, since the oxidation process will behave similarly in viruses with a similar morphological structure.

SARS-CoV-2 COVID-19 Coronavirus Disinfection

To understand Wellisair's efficacy against the pandemic COVID-19 Coronavirus (initially 2019-nCoV) that emerged in 2019 in Wuhan, one must understand the morphological structure of this type of virus, as well as its classification:

Alters the genetic information of viruses and bacteria (lipid peroxidation reaction):

CORONA VIRUS | WELLISAIR INDIA

Coronaviruses are in the Coronavirinae subfamily in the Coronaviridae family, in the order Nidovirales. They are divided into 4 VOC subgenres: Alpha, Beta, Delta and Gamma. COVID-19 corresponds to the SARS family, classified as Betacoronavirus of lineage "B", originating in bats.

VIRUS CLASSIFICATION | WELLISAIR INDIA

According to the genetic material, these viruses are included in group IV of the Baltimore classification, since the viral particle contains only one RNA chain of positive polarity linear single chain.

Structure of C

The diameter of the virus is around 60 to 200 nm, they have a nucleocapsid with helical symmetry and a lipid sheath that is derived from the membrane of the previously infected host cell. From these pods arise the characteristic projections in the form of a solar corona.

 

Due to the short time of the appearance of this strain, direct tests of the Wellisair technology against the virus have not been possible.

 

It has been possible to test a virus with a morphological structure similar to the coronavirus, such as the Respiratory Syncytial Virus (RSV). RSV is classified within Pneumoviruses, specifically in the Paramyxoviridae family, and even though it is not within the same family, this virus shares great similarities to COVID-19 as lipid membrane and glycoprotein projections.

mircroscopic structure | Wellisair India

The oxidation reactions (lipid oxidation and protein oxidation) that occur in the RSV are the same that they should have in COVID-19, so the elimination efficiency should be very similar.

Based on the results obtained with Wellisair in viruses with similar structures (RSV) to the COVID-19 Coronavirus, we can expect that the efficacy of our new technology will have an expected elimination result of an average of 92 to 99% depending on the relative humidity conditions.

Bibliographic Report University of Barcelona

The microbiology, virology and biotechnology section of the laboratory for contaminating viruses in water and food at the University of Barcelona has produced a bibliographic report on disinfection and the COVID-19 Coronavirus.

Coronaviruses more like SARS-CoV are easily inactivated with commonly used disinfectants, and are especially more susceptible to alcohol-based ones (such as OH hydroxyl radical technology).

Coronavirus has a morphology very similar to RSV respiratory syncytial virus tested by the University of Barcelona with a reduction power of 92 to 99% (dry/wet) in 2 hours.

Although ozone is an especially efficient disinfectant for RNA viruses, high concentrations are harmful to living beings and therefore not suitable for environments inhabited by humans.

In contrast, with the hydroxyl radicals OH generated by Wellisair, according to the results obtained in our laboratory, it is expected a similar inactivation of Coronavirus without the drawbacks of ozone toxicity.

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